Aura Clinic Singapore


Discover the Power of FDA Approved Polynucleotides : Increases skin’s Collagen by 60%, Elasticity by 22% and Hydration by 15%.

Polynucleotides stimulates collagen & cell growth, leaving your skin plump, dewy, and oh-so-youthful.

Benefits of Polynucleotides injectable treatments

This treatment is suitable for those with the following skin concerns:
  • Aging skin
  • Fine lines and wrinkles
  • Enlarged pores
  • Acne scars / surgical scars
  • Pigmentation
  • Sensitive skin
  • Dry and dehydrated skin
  • Dull skin
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Seeing is Believing

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What is Polynucleotide

We have the first and original polynucleotide (PN), a DNA fragment extracted from ethically bred Italian Trout Fish using the patented Highly Purified Technology (HPT). Polynucleotides are the latest tools in regenerative medicine that work on a cellular level to repair tissue and boost skin quality. Through a natural physiological process, it promotes skin bio-revitalization and collagen regeneration, restoring skin radiance, youthfulness, and elasticity.

Polynucleotides have been available in Europe since 2005 with US FDA approval and CE marked. With 70 years’ worth of research and more than 100 published clinical studies,  Mastelli Aesthetic perfected the HPT™ technology to ensure only the highest purification levels of PN are extracted, resulting in superior efficacy and safety compliance meeting the highest pharmaceutical standards.

What is Polynucleotides for?

  • Total Facial Bio-Revitalization to reverse skin ageing.
  • Softens and flattens acne scars, wrinkles and fine lines.
  • Minimizes skin pores.
  • Improves skin hydration & elasticity.
  • Improves skin radiance for a youthful glow.
Image of polynucleotides hitting the skin with text on its benefits

What are you waiting for? Sign up for a session of Polynucleotides today!

Illuminate Your Beauty Journey with Us

Frequently Asked Questions

How many sessions do I need?

Every person is unique. Some people may see a difference after the first session. In most cases, three sessions are required to attain the desired effects. 

Generally, patients require an average of 3 sessions, spaced 3-4 weeks apart to achieve desirable results.

An additional session is recommended in 6~12 months after a treatment protocol of 3 sessions.

How long is the procedure?

The treatment takes around 15-20 minutes.

Does it hurt?

Prior to the procedure, a topical aesthetic will be administered to help alleviate any pain or discomfort that the patient may feel throughout the treatment. As this is an injectable procedure, a needle sting level of discomfort is to be expected. Most patients report mild discomfort, but not unbearable pain. Each treatment takes about 10-20 minutes to complete.

What to expect during the treatment?

Our aim at AURA  is to make all procedures as comfortable as possible for our patients.

Topical numbing cream is applied to the skin before the start of treatment. As this is an injectable procedure, a needle sting level of discomfort is to be expected. Most patients report mild discomfort, but not unbearable pain. Each treatment takes about 10-20 minutes to complete.

It is important to choose an experienced doctor with injection control and precision to help reduce the trauma. Ultimately, this reduces bruising and downtime for the patient.

Is there any downtime?

Injection site marks, minor swelling, and bruising may appear. Depending on the person, downtime lasts 3-5 days.

When can I see the results from the treatment?

Collagen rebuilding and fibroblast proliferation are processes which take time. Some patients see noticeable results after the first session and that is mostly in terms of skin texture – better glow, brighter and smoother skin. In general, it takes about 2-4 weeks after your first session to begin enjoying the benefits of Polynucleotides. You might observe increased skin elasticity and lift due to the collagen stimulation, faded fine wrinkles and reduction in pore size.

Further improvements can be seen after the third session, with visible natural lifting and skin volumizing. The desirable outcome of youthful skin is typically after the full course.

Fibroblast production is a process that takes time. It is not instant, and it wouldn’t happen right after the treatment. It usually takes at least one week after the initial session to see effects, and improved results may be seen after 2 – 3 sessions.

Can Polynucleotides treatment be combined with other injectable treatments?

You certainly can. A multi-layer technique often produces superior outcomes. More information will be offered during your visit with one of our doctors.

Are there any contraindications?

We do not suggest this treatment for pregnant women or to anybody who is allergic to salmon or trout.

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